Sarah is having a heart attack.

What happens in the next hour will determine if she survives – and the quality of the rest of her life.

If Sarah had the option to receive earlier intervention in the ambulance following a 911 call, or in the ER, there could be an opportunity to reduce the risks to her clinical prognosis. That is why IMMEDIATE is developing IMT-358. FDA has designated IMT-358 as a Breakthrough Therapy for the treatment of acute coronary syndrome to reduce the risk of mortality, hospitalization for heart failure, and cardiac arrest.

7.5M

patients present with chest pain symptomatic of a possible heart attack (acute coronary syndrome) in the US each year.1 That’s one new patient every 4 seconds.

16%

of all deaths worldwide are due to ACS. That makes it the No. 1 cause of mortality.2

$188B

was the aggregate cost of treating ACS in 2008. By 2035 that cost is expected to double.3

IMT-358: An investigational drug under development by IMMEDIATE Therapeutics to be administered the first hours of a developing heart attack (i.e., ACS) to provide metabolic protection to the heart muscle, potentially minimizing cardiac damage and reducing cardiac instability that can lead to cardiac arrest. The efficacy of IMT-358 is under confirmation in a planned pivotal phase 3 trial.

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IMT-358 Begins When Time is Most Critical

Management Team

Atul Deshpande

Atul Deshpande

CHIEF EXECUTIVE OFFICER

  • Former Chief Strategy Officer & Head of Ops, Harbour BioMed with recent IPO experience raising $400M in 2020
  • Former Global Ops. Lead, Dupixent Franchise, Sanofi
  • Former Head, Asia Pacific R&D Strategy, Sanofi
  • Several Years Consulting Experience across Pharma Value Chain
Harry Selker

Harry Selker

ADVISOR

  • Executive Director, Institute for Clinical Research and Health Policy Studies; Pratt Diagnostic Center Primary Care Physician
  • Dean, Clinical and Translational Science Institute; Prof. of Medicine, Tufts University School of Medicine

James Udelson

ADVISOR

  • Chief, Division of Cardiology, Tufts Medical Center
  • Professor of Medicine and Radiology, Tufts Univ School of Medicine
  • Former Ad-hoc Member, FDA Cardiorenal AdCom
  • Ad-hoc Member of the Central and Peripheral Nervous System AdCom and the Medical Imaging Drugs AdCom
MEET OUR TEAM

IMT-358 Begins When Time is Most Critical

Notes

1. Rui P et al. National Hospital Ambulatory Medical Care Survey: 2017 emergency department summary tables. National Center for Health Statistics.

2. WHO CVDs Fact sheets (accessed on Jan 5, 2022); Selker HP et al. Ann Intern Med. 1998;129:845-855.

3. AHA Report: Cardiovascular Disease: A Costly Burden for America; World Heart Federation website (4/18/2021).